| 1 | Deadpool | 2016-02-09 | $58M | $375.74M | 6.48 |
| 2 | Deadpool 2 | 2018-05-10 | $110M | $343.06M | 3.12 |
| 3 | Logan | 2017-02-28 | $97M | $235.76M | 2.43 |
| 4 | The Martian | 2015-09-30 | $108M | $230.9M | 2.14 |
| 5 | Bohemian Rhapsody | 2018-10-24 | $52M | $220.2M | 4.23 |
| 6 | The Greatest Showman | 2017-12-20 | $84M | $174.05M | 2.07 |
| 7 | X-Men: Apocalypse | 2016-05-18 | $178M | $163.35M | 0.92 |
| 8 | War for the Planet of the Apes | 2017-07-11 | $150M | $151.84M | 1.01 |
| 9 | The Peanuts Movie | 2015-11-05 | $99M | $130.08M | 1.31 |
| 10 | Kingsman: The Secret Service | 2015-01-24 | $81M | $128.22M | 1.58 |
| 11 | Ford v Ferrari | 2019-11-13 | $98M | $119.72M | 1.23 |
| 12 | Spy | 2015-05-06 | $65M | $112.27M | 1.73 |
| 13 | Independence Day: Resurgence | 2016-06-22 | $165M | $107.12M | 0.65 |
| 14 | Murder on the Orient Express | 2017-11-03 | $55M | $104.4M | 1.90 |
| 15 | Kingsman: The Golden Circle | 2017-09-20 | $104M | $103.6M | 1.00 |
| 16 | Taken 3 | 2014-12-16 | $48M | $90.78M | 1.89 |
| 17 | Miss Peregrine's Home for Peculiar Children | 2016-09-27 | $110M | $88.43M | 0.80 |
| 18 | Alita: Battle Angel | 2019-01-31 | $170M | $88.24M | 0.52 |
| 19 | Ferdinand | 2017-12-09 | $111M | $84.3M | 0.76 |
| 20 | Maze Runner: The Scorch Trials | 2015-09-09 | $61M | $83.37M | 1.37 |
| 21 | The Post | 2017-12-22 | $50M | $82.51M | 1.65 |
| 22 | Alien: Covenant | 2017-05-09 | $97M | $78.45M | 0.81 |
| 23 | Dark Phoenix | 2019-06-05 | $200M | $70.85M | 0.35 |
| 24 | Spies in Disguise | 2019-12-04 | $100M | $66.76M | 0.67 |
| 25 | Ice Age: Collision Course | 2016-06-23 | $105M | $64.9M | 0.62 |
| 26 | Terminator: Dark Fate | 2019-10-23 | $185M | $64.6M | 0.35 |
| 27 | Why Him? | 2016-12-22 | $38M | $61.24M | 1.61 |
| 28 | Fantastic Four | 2015-08-05 | $120M | $58.75M | 0.49 |
| 29 | Maze Runner: The Death Cure | 2018-01-10 | $62M | $57.9M | 0.93 |
| 30 | The Predator | 2018-09-05 | $88M | $53.51M | 0.61 |
| 31 | Ad Astra | 2019-09-17 | $88M | $51.69M | 0.59 |
| 32 | Mike and Dave Need Wedding Dates | 2016-07-07 | $33M | $47.49M | 1.44 |
| 33 | Red Sparrow | 2018-02-28 | $69M | $46.74M | 0.68 |
| 34 | Snatched | 2017-05-03 | $42M | $46.5M | 1.11 |
| 35 | Night at the Museum: Secret of the Tomb | 2014-12-17 | $127M | $44.25M | 0.35 |
| 36 | Widows | 2018-11-06 | $42M | $42.4M | 1.01 |
| 37 | Love, Simon | 2018-02-16 | $17M | $40.82M | 2.40 |
| 38 | Breakthrough | 2019-04-10 | $14M | $40.71M | 2.91 |
| 39 | The Mountain Between Us | 2017-10-05 | $35M | $30.75M | 0.88 |
| 40 | Avatar | 2009-12-15 | $237M | $24.71M | 0.10 |
| 41 | Diary of a Wimpy Kid: The Long Haul | 2017-05-19 | $22M | $20.88M | 0.95 |
| 42 | Bad Times at the El Royale | 2018-10-04 | $32M | $17.79M | 0.56 |
| 43 | The Kid Who Would Be King | 2019-01-16 | $59M | $16.79M | 0.28 |
| 44 | Titanic | 1997-11-18 | $200M | $15.73M | 0.08 |
| 45 | The Darkest Minds | 2018-07-25 | $34M | $12.67M | 0.37 |
| 46 | Exodus: Gods and Kings | 2014-12-03 | $140M | $9.26M | 0.07 |
| 47 | A Cure for Wellness | 2017-02-15 | $40M | $8.08M | 0.20 |
| 48 | Kingsman: The Golden Circle | 2017-09-20 | $20M | $7.23M | 0.36 |
| 49 | Victor Frankenstein | 2015-11-10 | $40M | $5.92M | 0.15 |
| 50 | Morgan | 2016-09-01 | $8M | $3.88M | 0.49 |